List of pathogens currently detectable with AAMST.

Pathogen coverage of EVDL's respiratory panel is customizable: from single pathogen to multiple pathogens at one's choice. Pick from the test menu below and contact our sales team for your customized respiratory panel.

Early detection of other infectious diseases is as indispensable as rapid diagnosis of respiratory diseases. Taking sepsis as an example, such organ dysfunction is life-threatening. According to World Health Organization (WHO), "identifying and not underestimating the signs and symptoms listed above, along with the detection of some biomarkers (such as C reactive protein and procalcitonin), are crucial elements for early diagnosis of sepsis and the timely establishment of its appropriate clinical management. After early recognition, diagnostics to help identify a causal pathogen of infection leading to sepsis are important to guide targeted antimicrobial treatment.".* Likewise, meningitis, blood-borne disease and mosquito-borne disease etc. are some of the other common infectious diseases that are worth attention.

*https://www.who.int/news-room/fact-sheets/detail/sepsis

In the cancer field, rapid diagnostics can be helpful in early detection, rapid diagnosis and rapid treatment. According to World Health Organization (WHO), early diagnosis is particularly relevant to cancers of the breast, cervix, mouth, larynx, colon and rectum, and skin*. Detection of cancer specific alterations in proteins, DNA, and RNA in body fluids is important in guiding therapeutics and in monitoring the development of the diseases^. Diagnostic test is also a way to determine whether or not a patient has become resistant to certain drugs during the course the treatment.

*https://www.who.int/europe/news-room/fact-sheets/item/cancer-screening-and-early-detection-of-cancer

^https://www.sciencedirect.com/science/article/pii/B9780123694287000197

PCR testing is also applicable for the field of genomics to compare DNA sequences and to detect variations presented in biomarkers for some existing inherited diseases and/or those that are in development.

PCR test does not only diagnose if a person is infected or suffering from certain disease, but also plays an important role in the new trend of "precision medicine", sometimes also called "personalized medicine". Apart from guiding personalized treatment through a better understanding of genetic changes in a person, it also helps in monitoring if certain illness responds to a drug during treatment and if certain illness is returning (in the case of recurrence). New diagnostic technology will improve the overall healthcare management and patients' experience.

Common eye infections include red eye, conjunctivitis and corneal ulcer/keratitis*. Different eye infections could present with similar symptoms and could be from different sources, viral or bacterial. Taking infectious keratitis as an example, it may cause blindness and therefore rapid diagnosis and treatment play an important role, along with physician's evaluation based on signs and symptoms.

*https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003010/

As a platform technology, along with customized AAMC Cartridges, our AAMA Analzyer can be used in different medical specialties such as Immunology, Cardiovascular, Neurological, Paediatric, O&G (Obstetrics and Gynaecology) and Psychiatric etc.

Environmental testing can be broadly divided into two segments, one is testing how a product performs under different climatic conditions and/or mechanical stress, another one is testing on possible contaminants appeared in water, sewage, air and soil etc., and this is the area in which EVDL can provide a solution. Covid-19 pandemic has clearly demonstrated the importance of environmental testing and has assisted in identifying hidden infected persons through testing on sewage. Likewise, the recent emergence of Melioidosis, a disease caused by the bacterium Burkholderia pseudomallei, is another example. According to the information from Centre for Health Protection (CHP)*, this bacterium is widespread in soils and muddy water, particularly common in moist clay soils. It is endemic in Southeast Asia (e.g. Singapore and Thailand) and northern Australia. Rapid diagnostic will be crucial in taking quick action to block disease transmission.

*https://www.chp.gov.hk/en/healthtopics/content/24/101110.html

With the increasingly stringent safety and quality regulations in agriculture industry and higher expectation on quality products in the global market, the growth in agriculture testing continues in recent years. Agriculture testing consists of areas like DNA / protein testing, species identification, breeding and GMO (genetically modified organism) identification. Technology-wise, the agricultural testing services market is segmented into conventional and rapid. Rapid testing started to dominate since 2017 and continues to grow at a higher CAGR in 2022*. Key drivers of such growth in rapid testing include the demand on lower TAT (turnaround time), higher testing accuracy and sensitivity, as well as a wider coverage of bacteria to be tested. With Asia-Pacific being the fastest growing market^, EVDL is proud to be able to play a part in this region by providing its profound technology.

*https://www.marketsandmarkets.com/Market-Reports/agricultural-testing-market-203945812.html

^https://www.mordorintelligence.com/industry-reports/agricultural-testing-market

Applications in veterinary sector is wide and new diagnostic cartridge can be developed to cover OIE (named nowadays as World Organization for Animal Health, WOAH) listed pathogens for terrestrial (e.g. livestock and poultry) and aquatic animals (e.g. fishes and crustaceans), including but not limited to AIV, Newcastle Virus, IBV, FMDV, PRRSV, CSFV, ASFV, etc. According to recent research carried out by Research and Markets*, the livestock diagnostics market is expected to reach USD 2.02 Billion by 2028, growing at a CAGR of 8.2% during the forecast period (2021-2028). Key drivers for such growth include: rising demand for animal-derived food products, increasing prevalence of foodborne and zoonotic diseases, technological advancements in livestock diagnostic methods and favorable government initiatives. Rapid livestock diagnostic is one of the key parts in the food supply chain. Animals appear to be healthy could still be ill and carrying infectious disease. Transmission of infectious disease can happen among livestock rapidly and it easily causes massive slaughter and a loss in investment. Target applications include inspection and quarantine, farm surveillance and production safety. This is how and where rapid Point-of-Care Test (POCT) plays a role.

*https://www.researchandmarkets.com/reports/5011127/livestock-diagnostics-market-by-product#tag-pos-1

Food safety test is the last checkpoint along the food supply chain. Common food safety related pathogens include Norovirus, Staphylococcus sp. and Streptococcus sp., etc. Problems could possibly arise during food processing, from handling procedures, transportation or inappropriate storage condition. Apart from identifying the presence or absence of certain bacteria and fungi, there is also an increased demand in verifying if animal DNA appears in vegan products, or if substances causing food allergy exist in certain food products. Multiplex PCR can help differentiate different species in the same test, from plants to animals, and from fish to for example goat. Target applications cover inspection, market surveillance and production safety. Customized assays to cater different needs would be the trend and EVDL's diagnostic system has the distinctive features that the market desires. 

Veterinary diagnostic testing for animals is as important as other diagnostic tests for humans in healthcare assessments. Common testing includes blood testing, fecal testing and urinalysis. Similar to diagnostic test for humans, veterinarian and pet owners face problems like missed diagnoses, misdiagnoses, high testing cost and long testing lead-time (from 24 hours to weeks). 

According to recent research report from Markets and Markets*, the global veterinary diagnostics market is projected to reach USD 4.4 billion by 2027 from USD 2.8 billion in 2022, at a CAGR of 9.2%. With the outbreak of Covid-19 and the increased use of PCR test in ruling out Covid-19 virus in animals, Point-of-Care Testing (POCT) becomes an emerging market in veterinary diagnostic industry. As a platform technology, EVDL's solution can provide customized testing panels to suit different market needs.

*https://www.marketsandmarkets.com/Market-Reports/veterinary-diagnostics-market-26017452.html?gclid=Cj0KCQiAveebBhD_ARIsAFaAvrG_SWva4-N9uX9xY1cW6gR9IHUOj61jEreB9ISmeF-gKVIISLprPokaAtPDEALw_wcB

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info@emvdl.com